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Top 5 Scientific Studies

Useful Terms:

  • Cytotoxic = toxic to living cells.
  • Genotoxic = describes the property of chemical agents that damages the genetic information within a cell causing mutations, which may lead to cancer
  • Toxic = extremely harsh, malicious, or harmful to living organisms

1. Study: Levels of selected carcinogens and toxicants in vapour from electronic cigarettes

Conclusion: We found that the e-cigarette vapours contained some toxic substances. The levels of the toxicants were 9–450 times lower than in cigarette smoke and were, in many cases, comparable with trace amounts found in the reference product. Our findings are consistent with the idea that substituting tobacco cigarettes with e-cigarettes may substantially reduce exposure to selected tobacco-specific toxicants.

EcigResearch Note: In this study they compared ecigs and conventional cigarettes. What were the findings? The levels of toxicants were up to 450 times lower in ecigs than in conventional cigarettes. The scientists then go on to say “the idea that substituting tobacco cigarettes with e-cigarettes may substantially reduce exposure to selected tobacco-specific toxicants”.

2. Study: Comparative In Vitro Toxicity Profile of Electronic and Tobacco Cigarettes, Smokeless Tobacco and Nicotine Replacement Therapy Products: E-Liquids, Extracts and Collected Aerosols

Conclusion: The present findings indicate that neither the e-cig liquids and collected aerosols(ecig vapor), nor the extracts of the SLT and NRT products produce any meaningful toxic effects in four widely-applied in vitro test systems, in which the conventional cigarette smoke preparations, at comparable exposures, are markedly cytotoxic and genotoxic.

EcigResearch Note: In this study they found e-cig liquids and vapor produced no meaningful toxic effects. Then they tested conventional cigarettes and found cytotoxic and genotoxic exposure.

3. Study: Acute effects of electronic and tobacco cigarette smoking on complete blood count

Conclusion: We observed no effects of e-cigarettes on complete blood count. Tobacco cigarettes increased white blood cell, lymphocyte, and granulocyte counts.

EcigResearch Note: In this study they found e-cig use had no effect on complete blood count. Conventional cigarettes increased white blood cell, lymphocyte, and granulocyte counts.

4. Study: Immediate effects of electronic cigarette use on coronary circulation and blood carboxyhemoglobin levels: comparison with cigarette smoking

Conclusion: Cigarette smoking causes an acute elevation in carboxyhemoglobin levels (HbCO) and has immediate adverse effects on coronary circulation. On the contrary, no difference was observed in all parameters after ecig use in both smokers and ex-smokers. Research in this field should be intensified because EC may have the potential to significantly reduce the adverse health effects associated with smoking.

EcigResearch Note: In this study they found e-cig use had no effect on coronary circulation(blood circulation to the heart). On the other hand smoking 2 conventional cigarettes had negative effects on blood circulation to the heart.

5. Study: Effects of electronic cigarette use on the elastic properties of the ascending aorta in healthy subjects: comparison with the effects of tobacco cigarettes

Conclusion: Significantly decreased elasticity and elevated stiffness of ascending aorta was observed after smoking, confirming previous studies. However, no adverse effects were observed after using the EC(electronic cigarette). Research on ecigs should be intensified since they may be potentially useful in reducing the adverse vascular effects associated with smoking.

EcigResearch Note: The aorta is the main artery in the human body, originating from the left ventricle of the heart and extending down to the abdomen. This study showed using ecigs had no adverse effects on the aorta. The study did show that smoking conventional cigarettes had extremely negative effects on the aorta.